8.24.2011

Inositol Side Effects

Inositol is POSSIBLY SAFE for most adults. It can cause nausea, tiredness, headache, and dizziness.

Nausea


Fatigue

Headaches

Dizziness.

There are a few less common, but more serious, inositol side effects that you should report to your healthcare provider. These include but are not limited to:


Worsening of bipolar disorder (although this was reported in only one case and may have been caused by other factors)

Signs of an allergic reaction, such as:

Itching

Hives

A rash

Wheezing

Difficulty breathing

Swelling of the mouth or throat.

Some preliminary results of studies on high-dose inositol supplements show promising results for people suffering from problems such as bulimia, panic disorder, obsessive-compulsive disorder, agoraphobia, and unipolar and bipolar depression.[18][19][20][21]


In a single double-blind study on 13 patients, Myo-inositol (18 grams daily) has been found to reduce the symptoms of obsessive-compulsive disorder (OCD) significantly, with effectiveness equal to SSRIs and virtually without side-effects.[22] In a double-blind, controlled trial, myo-inositol (18 grams daily) was superior to fluvoxamine for decreasing the number of panic attacks and other side-effects.[20]

Patients suffering from clinical depression, in general, have decreased levels of inositol in their cerebrospinal fluid.[18][19] A double-blind, placebo-controlled study of depressed patients showed that a high dose of inositol (12 grams daily) resulted in significant improvement of symptoms, with no changes noted in liver, kidney, or hematological function.[18][19][21] A meta-analysis of randomized trials of inositol for depression was not able to determine if inositol is of benefit.[23]



Resources:
http://www.webmd.com/vitamins-supplements/ingredientmono-299-INOSITOL.aspx?activeIngredientId=299&activeIngredientName=INOSITOL

http://mental-health.emedtv.com/inositol/inositol-side-effects.html

http://en.wikipedia.org/wiki/Inositol

http://www.nutritional-supplements-health-guide.com/inositol-side-effects.html

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